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Uptake of tumor-derived microparticles induces metabolic reprogramming of macrophages in the early metastatic lung

Pre-metastatic niche formation is a critical step during the metastatic spread of cancer. One way by which primary tumors prime host cells at future metastatic sites is through the shedding of tumor-derived microparticles as a consequence of vascular sheer flow. However, it remains unclear how the u...

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Detalles Bibliográficos
Autores principales: Kersten, Kelly, You, Ran, Liang, Sophia, Tharp, Kevin M., Pollack, Joshua, Weaver, Valerie M., Krummel, Matthew F., Headley, Mark B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592447/
https://www.ncbi.nlm.nih.gov/pubmed/37261951
http://dx.doi.org/10.1016/j.celrep.2023.112582