Several cell-intrinsic effectors drive type I interferon-mediated restriction of HIV-1 in primary CD4(+) T cells

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Type I interferon (IFN) upregulates proteins that inhibit HIV within infected cells. Prior studies have identified IFN-stimulated genes (ISGs) that impede lab-adapted HIV in cell lines, yet the ISG(s) that mediate IFN restriction in HIV target cells, primary CD4(+) T cells, are unknown. Here, we int...

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Detalles Bibliográficos
Autores principales: Itell, Hannah L., Humes, Daryl, Overbaugh, Julie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592456/
https://www.ncbi.nlm.nih.gov/pubmed/37227817
http://dx.doi.org/10.1016/j.celrep.2023.112556

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592456/
https://www.ncbi.nlm.nih.gov/pubmed/37227817
http://dx.doi.org/10.1016/j.celrep.2023.112556

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