Distinct bidirectional regulation of LFA1 and α4β7 by Rap1 and integrin adaptors in T cells under shear flow

Bidirectional control of integrin activation plays crucial roles in cell adhesive behaviors, but how integrins are specifically regulated by inside-out and outside-in signaling has not been fully understood. Here, we report distinct bidirectional regulation of major lymphocyte homing receptors LFA1...

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Detalles Bibliográficos
Autores principales: Kamioka, Yuji, Ueda, Yoshihiro, Kondo, Naoyuki, Tokuhiro, Keizo, Ikeda, Yoshiki, Bergmeier, Wolfgang, Kinashi, Tatsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592472/
https://www.ncbi.nlm.nih.gov/pubmed/37267105
http://dx.doi.org/10.1016/j.celrep.2023.112580

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592472/
https://www.ncbi.nlm.nih.gov/pubmed/37267105
http://dx.doi.org/10.1016/j.celrep.2023.112580

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