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Spatial single-cell sequencing of meiosis I arrested oocytes indicates acquisition of maternal transcripts from the soma

Maternal RNAs are stored from minutes to decades in oocytes throughout meiosis I arrest in a transcriptionally quiescent state. Recent reports, however, propose a role for nascent transcription in arrested oocytes. Whether arrested oocytes launch nascent transcription in response to environmental or...

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Detalles Bibliográficos
Autores principales: Trimmer, Kenneth A., Zhao, Peisen, Seemann, Jacob, Chen, Shin-Yu, Mondal, Sudip, Ben-Yakar, Adela, Arur, Swathi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592488/
https://www.ncbi.nlm.nih.gov/pubmed/37227820
http://dx.doi.org/10.1016/j.celrep.2023.112544