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Single-nucleus resolution mapping of the adult C. elegans and its application to elucidate inter- and trans-generational response to alcohol

Single-cell transcriptomic platforms provide an opportunity to map an organism’s response to environmental cues with high resolution. Here, we applied single-nucleus RNA sequencing (snRNA-seq) to establish the tissue and cell type-resolved transcriptome of the adult C. elegans and characterize the i...

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Detalles Bibliográficos
Autores principales: Truong, Lisa, Chen, Yen-Wei, Barrere-Cain, Rio, Levenson, Max T., Shuck, Karissa, Xiao, Wen, da Veiga Beltrame, Eduardo, Panter, Blake, Reich, Ella, Sternberg, Paul W., Yang, Xia, Allard, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592506/
https://www.ncbi.nlm.nih.gov/pubmed/37227821
http://dx.doi.org/10.1016/j.celrep.2023.112535