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Heat shock factor 1 (HSF1) specifically potentiates c-MYC-mediated transcription independently of the canonical heat shock response

Despite its pivotal roles in biology, how the transcriptional activity of c-MYC is tuned quantitatively remains poorly defined. Here, we show that heat shock factor 1 (HSF1), the master transcriptional regulator of the heat shock response, acts as a prime modifier of the c-MYC-mediated transcription...

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Detalles Bibliográficos
Autores principales: Xu, Meng, Lin, Ling, Ram, Babul Moni, Shriwas, Omprakash, Chuang, Kun-Han, Dai, Siyuan, Su, Kuo-Hui, Tang, Zijian, Dai, Chengkai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592515/
https://www.ncbi.nlm.nih.gov/pubmed/37224019
http://dx.doi.org/10.1016/j.celrep.2023.112557