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Heat shock factor 1 (HSF1) specifically potentiates c-MYC-mediated transcription independently of the canonical heat shock response
Despite its pivotal roles in biology, how the transcriptional activity of c-MYC is tuned quantitatively remains poorly defined. Here, we show that heat shock factor 1 (HSF1), the master transcriptional regulator of the heat shock response, acts as a prime modifier of the c-MYC-mediated transcription...
Autores principales: | Xu, Meng, Lin, Ling, Ram, Babul Moni, Shriwas, Omprakash, Chuang, Kun-Han, Dai, Siyuan, Su, Kuo-Hui, Tang, Zijian, Dai, Chengkai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592515/ https://www.ncbi.nlm.nih.gov/pubmed/37224019 http://dx.doi.org/10.1016/j.celrep.2023.112557 |
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