Shikonin promotes hypertrophic scar repair by autophagy of hypertrophic scar-derived fibroblasts

PURPOSE: To investigate the Shikonin (SHI) induce autophagy of hypertrophic scar-derived fibroblasts (HSFs) and the mechanism of which in repairing hypertrophic scar. METHODS: This study showed that SHI induced autophagy from HSFs and repaired skin scars through the AMPK/mTOR pathway. Alamar Blue an...

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Detalles Bibliográficos
Autores principales: Zhang, Qing, Wang, Maomao, Deng, Xingwang, Zhao, Dan, Zhao, Fang, Xiao, Jinli, Ma, Jiaxiang, Pan, Xiaoliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592587/
https://www.ncbi.nlm.nih.gov/pubmed/37878984
http://dx.doi.org/10.1590/acb384623

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592587/
https://www.ncbi.nlm.nih.gov/pubmed/37878984
http://dx.doi.org/10.1590/acb384623

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