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The impact of common variants on gene expression in the human brain: from RNA to protein to schizophrenia risk

BACKGROUND: The impact of genetic variants on gene expression has been intensely studied at the transcription level, yielding in valuable insights into the association between genes and the risk of complex disorders, such as schizophrenia (SCZ). However, the downstream impact of these variants and t...

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Detalles Bibliográficos
Autores principales: Liang, Qiuman, Jiang, Yi, Shieh, Annie W., Zhou, Dan, Chen, Rui, Wang, Feiran, Xu, Meng, Niu, Mingming, Wang, Xusheng, Pinto, Dalila, Wang, Yue, Cheng, Lijun, Vadukapuram, Ramu, Zhang, Chunling, Grennan, Kay, Giase, Gina, White, Kevin P, Peng, Junmin, Li, Bingshan, Liu, Chunyu, Chen, Chao, Wang, Sidney H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592607/
https://www.ncbi.nlm.nih.gov/pubmed/37873195
http://dx.doi.org/10.1101/2023.06.04.543603