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Remyelination protects neurons from DLK-mediated neurodegeneration

Chronic demyelination is theorized to contribute to neurodegeneration and drive progressive disability in demyelinating diseases like multiple sclerosis. Here, we describe two genetic mouse models of inducible demyelination, one distinguished by effective remyelination, and the other by remyelinatio...

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Detalles Bibliográficos
Autores principales: Duncan, Greg J, Ingram, Samantha D, Emberley, Katie, Hill, Jo, Cordano, Christian, Abdelhak, Ahmed, McCane, Michael, Jabassini, Nora, Ananth, Kirtana, Ferrara, Skylar J., Stedelin, Brittany, Sivyer, Benjamin, Aicher, Sue A., Scanlan, Thomas, Watkins, Trent A, Mishra, Anusha, Nelson, Jonathan, Green, Ari J., Emery, Ben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592610/
https://www.ncbi.nlm.nih.gov/pubmed/37873342
http://dx.doi.org/10.1101/2023.09.30.560267