TMEM65 regulates NCLX-dependent mitochondrial calcium efflux

The balance between mitochondrial calcium ((m)Ca(2+)) uptake and efflux regulates ATP production, but if perturbed causes energy starvation or (m)Ca(2+) overload and cell death. The mitochondrial sodium-calcium exchanger, NCLX, is a critical route of (m)Ca(2+) efflux in excitable tissues, such as th...

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Detalles Bibliográficos
Autores principales: Garbincius, Joanne F., Salik, Oniel, Cohen, Henry M., Choya-Foces, Carmen, Mangold, Adam S., Makhoul, Angelina D., Schmidt, Anna E., Khalil, Dima Y., Doolittle, Joshua J., Wilkinson, Anya S., Murray, Emma K., Lazaropoulos, Michael P., Hildebrand, Alycia N., Tomar, Dhanendra, Elrod, John W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592617/
https://www.ncbi.nlm.nih.gov/pubmed/37873405
http://dx.doi.org/10.1101/2023.10.06.561062

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592617/
https://www.ncbi.nlm.nih.gov/pubmed/37873405
http://dx.doi.org/10.1101/2023.10.06.561062

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