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Controlling Genome Topology with Sequences that Trigger Post-replication Gap Formation During Replisome Passage: The E. coli RRS Elements

We report that the Escherichia coli chromosome includes novel GC-rich genomic structural elements that trigger formation of post-replication gaps upon replisome passage. The two nearly perfect 222 bp repeats, designated Replication Risk Sequences or RRS, are each 650 kbp from the terminus sequence d...

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Detalles Bibliográficos
Autores principales: Pham, Phuong, Wood, Elizabeth A., Dunbar, Emma L., Cox, Michael M., Goodman, Myron F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592627/
https://www.ncbi.nlm.nih.gov/pubmed/37873128
http://dx.doi.org/10.1101/2023.10.01.560376