Development and validation of an automated assay for anti-drug-antibodies in rat serum

The potential immunogenicity of therapeutic human and humanized monoclonal antibodies (mAb) is a significant concern, and so preclinical testing of therapeutic mAbs routinely includes assessment of anti-drug antibody (ADA) induction. Here, we report the development of automated screening and confirm...

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Detalles Bibliográficos
Autores principales: Terrell, Kristy A., Sempowski, Gregory D., Macintyre, Andrew N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592652/
https://www.ncbi.nlm.nih.gov/pubmed/37120133
http://dx.doi.org/10.1016/j.slast.2023.04.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592652/
https://www.ncbi.nlm.nih.gov/pubmed/37120133
http://dx.doi.org/10.1016/j.slast.2023.04.001

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