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Development and validation of an automated assay for anti-drug-antibodies in rat serum

The potential immunogenicity of therapeutic human and humanized monoclonal antibodies (mAb) is a significant concern, and so preclinical testing of therapeutic mAbs routinely includes assessment of anti-drug antibody (ADA) induction. Here, we report the development of automated screening and confirm...

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Detalles Bibliográficos
Autores principales:	Terrell, Kristy A., Sempowski, Gregory D., Macintyre, Andrew N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592652/ https://www.ncbi.nlm.nih.gov/pubmed/37120133 http://dx.doi.org/10.1016/j.slast.2023.04.001

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