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Analyses of allele age and fitness impact reveal human beneficial alleles to be older than neutral controls

A classic population genetic prediction is that alleles experiencing directional selection should swiftly traverse allele frequency space, leaving detectable reductions in genetic variation in linked regions. However, despite this expectation, identifying clear footprints of beneficial allele passag...

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Detalles Bibliográficos
Autores principales: Pivirotto, Alyssa M., Platt, Alexander, Patel, Ravi, Kumar, Sudhir, Hey, Jody
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592680/
https://www.ncbi.nlm.nih.gov/pubmed/37873438
http://dx.doi.org/10.1101/2023.10.09.561569