Cargando…

ASCT2 is the primary serine transporter in cancer cells

The non-essential amino acid serine is a critical nutrient for cancer cells due to its diverse biosynthetic functions. While some tumors can synthesize serine de novo, others are auxotrophic for serine and therefore reliant on the uptake of exogenous serine. Importantly, however, the transporter(s)...

Descripción completa

Detalles Bibliográficos
Autores principales: Conger, Kelly O., Chidley, Christopher, Ozgurses, Mete Emir, Zhao, Huiping, Kim, Yumi, Semina, Svetlana E., Burns, Philippa, Rawat, Vipin, Sheldon, Ryan, Ben-Sahra, Issam, Frasor, Jonna, Sorger, Peter K., DeNicola, Gina M., Coloff, Jonathan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592681/
https://www.ncbi.nlm.nih.gov/pubmed/37873453
http://dx.doi.org/10.1101/2023.10.09.561530