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mRNA cap-binding protein eIF4E1 is a novel regulator of Toxoplasma gondii latency

The protozoan parasite Toxoplasma gondii causes serious opportunistic disease due to its ability to persist in patients as latent tissue cysts. The molecular mechanisms coordinating conversion between proliferative parasites (tachyzoites) and dormant cysts (bradyzoites) are not fully understood. We...

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Detalles Bibliográficos
Autores principales: Holmes, Michael J., Bastos, Matheus S., Dey, Vishakha, Severo, Vanessa, Wek, Ronald C., Sullivan, William J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592687/
https://www.ncbi.nlm.nih.gov/pubmed/37873335
http://dx.doi.org/10.1101/2023.10.09.561274