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Functional genomics reveals an off-target dependency of drug synergy in gastric cancer therapy
The rational combination of anticancer agents is critical to improving patient outcomes in cancer. Nonetheless, most combination regimens in the clinic result from empirical methodologies disregarding insight into the mechanism of action and missing the opportunity to improve therapy outcomes increm...
Autores principales: | Leylek, Ozen, Honeywell, Megan E., Lee, Michael J., Hemann, Michael T., Ozcan, Gulnihal |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592690/ https://www.ncbi.nlm.nih.gov/pubmed/37873383 http://dx.doi.org/10.1101/2023.10.07.561351 |
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