The fitness cost of spurious phosphorylation

The fidelity of signal transduction requires the binding of regulatory molecules to their cognate targets. However, the crowded cell interior risks off-target interactions between proteins that are functionally unrelated. How such off-target interactions impact fitness is not generally known, but qu...

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Detalles Bibliográficos
Autores principales: Bradley, David, Hogrebe, Alexander, Dandage, Rohan, Dubé, Alexandre K, Leutert, Mario, Dionne, Ugo, Chang, Alexis, Villén, Judit, Landry, Christian R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592693/
https://www.ncbi.nlm.nih.gov/pubmed/37873463
http://dx.doi.org/10.1101/2023.10.08.561337

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592693/
https://www.ncbi.nlm.nih.gov/pubmed/37873463
http://dx.doi.org/10.1101/2023.10.08.561337

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