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The fitness cost of spurious phosphorylation
The fidelity of signal transduction requires the binding of regulatory molecules to their cognate targets. However, the crowded cell interior risks off-target interactions between proteins that are functionally unrelated. How such off-target interactions impact fitness is not generally known, but qu...
Autores principales: | Bradley, David, Hogrebe, Alexander, Dandage, Rohan, Dubé, Alexandre K, Leutert, Mario, Dionne, Ugo, Chang, Alexis, Villén, Judit, Landry, Christian R |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592693/ https://www.ncbi.nlm.nih.gov/pubmed/37873463 http://dx.doi.org/10.1101/2023.10.08.561337 |
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