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An in vitro platform for quantifying cell cycle phase lengths in primary human intestinal stem cells

BACKGROUND AND AIMS: The intestinal epithelium exhibits dynamic control of cell cycle phase lengths, yet no experimental platform exists for directly analyzing cell cycle phases in living human intestinal stem cells (ISCs). Here, we develop primary human ISC lines with two different reporter constru...

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Detalles Bibliográficos
Autores principales: Cotton, Michael J, Ariel, Pablo, Chen, Kaiwen, Walcott, Vanessa A, Dixit, Michelle, Breau, Keith A, Hinesley, Caroline M, Kedziora, Kasia, Tang, Cynthia Y, Zheng, Anna, Magness, Scott T, Burclaff, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592697/
https://www.ncbi.nlm.nih.gov/pubmed/37873351
http://dx.doi.org/10.1101/2023.10.09.561410