Double-strand break repair-associated intragenic deletions and tandem duplications suggest the architecture of the repair replication fork

Double-strand break (DSB) repair is associated with a 1000-fold increase in mutations compared to normal replication of the same sequences. In budding yeast, repair of an HO endonuclease-induced DSB at the MATα locus can be repaired by using a homologous, heterochromatic HMR::Kl-URA3 donor harboring...

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Detalles Bibliográficos
Autores principales: Dalin, Simona, Webster, Sophie, Sugawara, Neal, Zhang, Shu, Wu, Qiuqin, Cui, Tracy, Liang, Victoria, Beroukhim, Rameen, Haber, James E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592705/
https://www.ncbi.nlm.nih.gov/pubmed/37873277
http://dx.doi.org/10.1101/2023.10.09.561461

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592705/
https://www.ncbi.nlm.nih.gov/pubmed/37873277
http://dx.doi.org/10.1101/2023.10.09.561461

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