Inputs to the locus coeruleus from the periaqueductal gray and rostroventral medulla shape opioid-mediated descending pain modulation

The supraspinal descending pain modulatory system (DPMS) shapes pain perception via monoaminergic modulation of sensory information in the spinal cord. However, the role and synaptic mechanisms of descending noradrenergic signaling remain unclear. Here, we establish that noradrenergic neurons of the...

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Detalles Bibliográficos
Autores principales: Lubejko, Susan T., Livrizzi, Giulia, Patel, Janki, Yung, Jean C., Yaksh, Tony L., Banghart, Matthew R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592708/
https://www.ncbi.nlm.nih.gov/pubmed/37873091
http://dx.doi.org/10.1101/2023.10.10.561768

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592708/
https://www.ncbi.nlm.nih.gov/pubmed/37873091
http://dx.doi.org/10.1101/2023.10.10.561768

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