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Inputs to the locus coeruleus from the periaqueductal gray and rostroventral medulla shape opioid-mediated descending pain modulation
The supraspinal descending pain modulatory system (DPMS) shapes pain perception via monoaminergic modulation of sensory information in the spinal cord. However, the role and synaptic mechanisms of descending noradrenergic signaling remain unclear. Here, we establish that noradrenergic neurons of the...
Autores principales: | Lubejko, Susan T., Livrizzi, Giulia, Patel, Janki, Yung, Jean C., Yaksh, Tony L., Banghart, Matthew R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592708/ https://www.ncbi.nlm.nih.gov/pubmed/37873091 http://dx.doi.org/10.1101/2023.10.10.561768 |
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