Cell specific single viral vector CRISPR/Cas9 editing and genetically encoded tool delivery in the central and peripheral nervous systems

Gene manipulation strategies using germline knockout, conditional knockout, and more recently CRISPR/Cas9 are crucial tools for advancing our understanding of the nervous system. However, traditional gene knockout approaches can be costly and time consuming, may lack cell-type specificity, and can i...

Descripción completa

Detalles Bibliográficos
Autores principales: Moffa, Jamie C., Bland, India N., Tooley, Jessica R., Kalyanaraman, Vani, Heitmeier, Monique, Creed, Meaghan C., Copits, Bryan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592710/
https://www.ncbi.nlm.nih.gov/pubmed/37873336
http://dx.doi.org/10.1101/2023.10.10.561249

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592710/
https://www.ncbi.nlm.nih.gov/pubmed/37873336
http://dx.doi.org/10.1101/2023.10.10.561249

Ejemplares similares