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Cell specific single viral vector CRISPR/Cas9 editing and genetically encoded tool delivery in the central and peripheral nervous systems
Gene manipulation strategies using germline knockout, conditional knockout, and more recently CRISPR/Cas9 are crucial tools for advancing our understanding of the nervous system. However, traditional gene knockout approaches can be costly and time consuming, may lack cell-type specificity, and can i...
Autores principales: | Moffa, Jamie C., Bland, India N., Tooley, Jessica R., Kalyanaraman, Vani, Heitmeier, Monique, Creed, Meaghan C., Copits, Bryan A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592710/ https://www.ncbi.nlm.nih.gov/pubmed/37873336 http://dx.doi.org/10.1101/2023.10.10.561249 |
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