GPN-MSA: an alignment-based DNA language model for genome-wide variant effect prediction

Whereas protein language models have demonstrated remarkable efficacy in predicting the effects of missense variants, DNA counterparts have not yet achieved a similar competitive edge for genome-wide variant effect predictions, especially in complex genomes such as that of humans. To address this ch...

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Detalles Bibliográficos
Autores principales: Benegas, Gonzalo, Albors, Carlos, Aw, Alan J., Ye, Chengzhong, Song, Yun S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592768/
https://www.ncbi.nlm.nih.gov/pubmed/37873118
http://dx.doi.org/10.1101/2023.10.10.561776

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592768/
https://www.ncbi.nlm.nih.gov/pubmed/37873118
http://dx.doi.org/10.1101/2023.10.10.561776

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