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GPN-MSA: an alignment-based DNA language model for genome-wide variant effect prediction
Whereas protein language models have demonstrated remarkable efficacy in predicting the effects of missense variants, DNA counterparts have not yet achieved a similar competitive edge for genome-wide variant effect predictions, especially in complex genomes such as that of humans. To address this ch...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592768/ https://www.ncbi.nlm.nih.gov/pubmed/37873118 http://dx.doi.org/10.1101/2023.10.10.561776 |