CCR5 promotes the migration of CD8(+) T cells to the leishmanial lesions

Cytolytic CD8(+) T cells mediate immunopathology in cutaneous leishmaniasis without controlling parasites. Here, we identify factors involved in CD8(+) T cell migration to the lesion that could be targeted to ameliorate disease severity. CCR5 was the most highly expressed chemokine receptor in patie...

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Detalles Bibliográficos
Autores principales: Sacramento, Laís Amorim, Amorim, Camila Farias, Lombana, Claudia G., Beiting, Daniel, Novais, Fernanda, Carvalho, Lucas P., Carvalho, Edgar M., Scott, Phillip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592772/
https://www.ncbi.nlm.nih.gov/pubmed/37873253
http://dx.doi.org/10.1101/2023.10.10.561700

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592772/
https://www.ncbi.nlm.nih.gov/pubmed/37873253
http://dx.doi.org/10.1101/2023.10.10.561700

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