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CCR5 promotes the migration of CD8(+) T cells to the leishmanial lesions
Cytolytic CD8(+) T cells mediate immunopathology in cutaneous leishmaniasis without controlling parasites. Here, we identify factors involved in CD8(+) T cell migration to the lesion that could be targeted to ameliorate disease severity. CCR5 was the most highly expressed chemokine receptor in patie...
Autores principales: | Sacramento, Laís Amorim, Amorim, Camila Farias, Lombana, Claudia G., Beiting, Daniel, Novais, Fernanda, Carvalho, Lucas P., Carvalho, Edgar M., Scott, Phillip |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592772/ https://www.ncbi.nlm.nih.gov/pubmed/37873253 http://dx.doi.org/10.1101/2023.10.10.561700 |
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