Identification of a binding site for bupropion in Gloeobacter violaceus ligand-gated ion channel

Bupropion is an atypical antidepressant and smoking cessation drug which causes adverse effects such as insomnia, irritability, and anxiety. Bupropion inhibits dopamine and norepinephrine reuptake transporters and eukaryotic cation-conducting pentameric ligand-gated ion channels (pLGICs), such as ni...

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Detalles Bibliográficos
Autores principales: Pirayesh, Elham, Do, Hoa Quynh, Ferreira, Garren, Pandhare, Akash, Gallardo, Zackary Ryan, Jansen, Michaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592773/
https://www.ncbi.nlm.nih.gov/pubmed/37873398
http://dx.doi.org/10.1101/2023.10.09.561596

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592773/
https://www.ncbi.nlm.nih.gov/pubmed/37873398
http://dx.doi.org/10.1101/2023.10.09.561596

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