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Measuring conformational equilibria in allosteric proteins with time-resolved tmFRET
Proteins are the workhorses of biology, orchestrating a myriad of cellular functions through intricate conformational changes. Protein allostery, the phenomenon where binding of ligands or environmental changes induce conformational rearrangements in the protein, is fundamental to these processes. W...
Autores principales: | Zagotta, William N., Evans, Eric G. B., Eggan, Pierce, Tessmer, Maxx H., Shaffer, Kyle D., Petersson, E. James, Stoll, Stefan, Gordon, Sharona E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592786/ https://www.ncbi.nlm.nih.gov/pubmed/37873384 http://dx.doi.org/10.1101/2023.10.09.561594 |
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