The fatty liver disease-causing protein PNPLA3-I148M alters lipid droplet-Golgi dynamics

Non-alcoholic fatty liver disease (NAFLD), recently renamed metabolic dysfunction-associated steatotic liver disease (MASLD), is a progressive metabolic disorder that begins with aberrant triglyceride accumulation in the liver and can lead to cirrhosis and cancer. A common variant in the gene PNPLA3...

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Detalles Bibliográficos
Autores principales: Sherman, David J., Liu, Lei, Mamrosh, Jennifer L., Xie, Jiansong, Ferbas, John, Lomenick, Brett, Ladinsky, Mark S., Verma, Rati, Rulifson, Ingrid C., Deshaies, Raymond J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592801/
https://www.ncbi.nlm.nih.gov/pubmed/37873239
http://dx.doi.org/10.1101/2023.10.13.562302

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592801/
https://www.ncbi.nlm.nih.gov/pubmed/37873239
http://dx.doi.org/10.1101/2023.10.13.562302

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