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Reprogramming megakaryocytes to engineer platelets as delivery vehicles

We developed a method for the efficient generation of engineered platelets that can be filled with any recombinant therapeutic protein during the differentiation process by reprogramming megakaryocytes, the progenitor cells of platelets. To demonstrate the versatility of this approach, we loaded cyt...

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Detalles Bibliográficos
Autores principales: Javdan, Shwan B., Islam, Farhana, Deans, Tara L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592833/
https://www.ncbi.nlm.nih.gov/pubmed/37873465
http://dx.doi.org/10.1101/2023.10.13.562311