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Reprogramming megakaryocytes to engineer platelets as delivery vehicles
We developed a method for the efficient generation of engineered platelets that can be filled with any recombinant therapeutic protein during the differentiation process by reprogramming megakaryocytes, the progenitor cells of platelets. To demonstrate the versatility of this approach, we loaded cyt...
Autores principales: | Javdan, Shwan B., Islam, Farhana, Deans, Tara L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592833/ https://www.ncbi.nlm.nih.gov/pubmed/37873465 http://dx.doi.org/10.1101/2023.10.13.562311 |
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