Inferring B cell phylogenies from paired heavy and light chain BCR sequences with Dowser

Antibodies are vital to human immune responses and are composed of genetically variable heavy and light chains. These structures are initially expressed as B cell receptors (BCRs). BCR diversity is shaped through somatic hypermutation and selection during immune responses. This evolutionary process...

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Detalles Bibliográficos
Autores principales: Jensen, Cole G., Sumner, Jacob A., Kleinstein, Steven H., Hoehn, Kenneth B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592837/
https://www.ncbi.nlm.nih.gov/pubmed/37873135
http://dx.doi.org/10.1101/2023.09.29.560187

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592837/
https://www.ncbi.nlm.nih.gov/pubmed/37873135
http://dx.doi.org/10.1101/2023.09.29.560187

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