Activation of automethylated PRC2 by dimerization on chromatin

Polycomb Repressive Complex 2 (PRC2) is an epigenetic regulator that trimethylates lysine 27 of histone 3 (H3K27me3) and is essential for embryonic development and cellular differentiation. H3K27me3 is associated with transcriptionally repressed chromatin and is established when PRC2 is allosterical...

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Detalles Bibliográficos
Autores principales: Sauer, Paul V., Pavlenko, Egor, Cookis, Trinity, Zirden, Linda C., Renn, Juliane, Singhal, Ankush, Hunold, Pascal, Hoehne, Michaela N., van Ray, Olivia, Hänsel-Hertsch, Robert, Sanbonmatsu, Karissa Y., Nogales, Eva, Poepsel, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592840/
https://www.ncbi.nlm.nih.gov/pubmed/37873121
http://dx.doi.org/10.1101/2023.10.12.562141

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592840/
https://www.ncbi.nlm.nih.gov/pubmed/37873121
http://dx.doi.org/10.1101/2023.10.12.562141

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