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Vps18 contributes to phagosome membrane integrity in Mycobacterium tuberculosis-infected macrophages

Mycobacterium tuberculosis (Mtb) has evolved to be exquisitely adapted to survive within host macrophages. The capacity to damage the phagosomal membrane has emerged as central to Mtb virulence. While Mtb factors driving membrane damage have been described, host factors that repair that damage to co...

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Detalles Bibliográficos
Autores principales: Jani, Charul, Marsh, Amanda, Uchil, Pooja, Jain, Neha, Baskir, Zach R., Glover, Owen T., Root, David E., Doench, John G., Barczak, Amy K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592876/
https://www.ncbi.nlm.nih.gov/pubmed/37873319
http://dx.doi.org/10.1101/2023.10.01.560397