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Pulses of RhoA Signaling Stimulate Actin Polymerization and Flow in Protrusions to Drive Collective Cell Migration

In animals, cells often move as collectives to shape organs, close wounds, or—in the case of disease—metastasize. To accomplish this, cells need to generate force to propel themselves forward. The motility of singly migrating cells is driven largely by an interplay between Rho GTPase signaling and t...

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Detalles Bibliográficos
Autores principales: Qian, Weiyi, Yamaguchi, Naoya, Lis, Patrycja, Cammer, Michael, Knaut, Holger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592895/
https://www.ncbi.nlm.nih.gov/pubmed/37873192
http://dx.doi.org/10.1101/2023.10.03.560679