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Non-canonical activation of IRE1α during Candida albicans infection enhances macrophage fungicidal activity

Infection by intracellular pathogens can trigger activation of the IRE1α branch of the unfolded protein response (UPR), which then modulates innate immunity and infection outcomes during bacterial or viral infection. However, the mechanisms by which infection activates IRE1α have not been fully eluc...

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Detalles Bibliográficos
Autores principales: McFadden, Michael J., Reynolds, Mack B., Michmerhuizen, Britton C, Anderson, Faith M., O’Riordan, Mary X.D., O’Meara, Teresa R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592910/
https://www.ncbi.nlm.nih.gov/pubmed/37873171
http://dx.doi.org/10.1101/2023.10.02.560560