Accurate cryo-EM protein particle picking by integrating the foundational AI image segmentation model and specialized U-Net

Cryo-electron microscopy (cryo-EM) has revolutionized the field of structural biology by enabling the precise determination of large protein structures. Picking protein particles in cryo-EM micrographs (images) is a crucial step in the cryo-EM-based structure determination. However, existing methods...

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Detalles Bibliográficos
Autores principales: Gyawali, Rajan, Dhakal, Ashwin, Wang, Liguo, Cheng, Jianlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592924/
https://www.ncbi.nlm.nih.gov/pubmed/37873264
http://dx.doi.org/10.1101/2023.10.02.560572

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592924/
https://www.ncbi.nlm.nih.gov/pubmed/37873264
http://dx.doi.org/10.1101/2023.10.02.560572

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