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Targeted inhibition of BET proteins in HPV-16 associated head and neck squamous cell carcinoma reveals heterogeneous transcription response

Integrated human papillomavirus (HPV-16) associated head and neck squamous cell carcinoma (HNSCC) tumors have worse survival outcomes compared to episomal HPV-16 HNSCC tumors. Therefore, there is a need to differentiate treatment for HPV-16 integrated HNSCC from other viral forms. We analyzed TCGA d...

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Detalles Bibliográficos
Autores principales: Rao, Aakarsha, Ni, Zijian, Suresh, Dhruthi, Mohanty, Chitrasen, Wang, Albert R., Lee, Denis L, Nickel, Kwangok P., Varambally, Sooryanarayana Randall J., Lambert, Paul F., Kendziorski, Christina, Iyer, Gopal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592929/
https://www.ncbi.nlm.nih.gov/pubmed/37873389
http://dx.doi.org/10.1101/2023.10.02.560587