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Single-cell chromatin state transitions during epigenetic memory formation

Repressive chromatin modifications are thought to compact chromatin to silence transcription. However, it is unclear how chromatin structure changes during silencing and epigenetic memory formation. We measured gene expression and chromatin structure in single cells after recruitment and release of...

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Detalles Bibliográficos
Autores principales: Fujimori, Taihei, Rios-Martinez, Carolina, Thurm, Abby R., Hinks, Michaela M., Doughty, Benjamin R., Sinha, Joydeb, Le, Derek, Hafner, Antonina, Greenleaf, William J., Boettiger, Alistair N., Bintu, Lacramioara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592931/
https://www.ncbi.nlm.nih.gov/pubmed/37873344
http://dx.doi.org/10.1101/2023.10.03.560616