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Loss of STIM2 in colorectal cancer drives growth and metastasis through metabolic reprogramming and PERK-ATF4 endoplasmic reticulum stress pathway
The endoplasmic reticulum (ER) stores large amounts of calcium (Ca(2+)), and the controlled release of ER Ca(2+) regulates a myriad of cellular functions. Although altered ER Ca(2+) homeostasis is known to induce ER stress, the mechanisms by which ER Ca(2+) imbalance activate ER stress pathways are...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592933/ https://www.ncbi.nlm.nih.gov/pubmed/37873177 http://dx.doi.org/10.1101/2023.10.02.560521 |