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Cytochrome P450 and Epoxide Hydrolase Metabolites in Aβ and tau-induced Neurodegeneration: Insights from Caenorhabditis elegans

This study aims to uncover potent cytochrome P450 (CYP) and epoxide hydrolase (EH) metabolites implicated in Aβ and/or tau-induced neurodegeneration, independent of neuroinflammation, by utilizing Caenorhabditis elegans (C. elegans) as a model organism. Our research reveals that Aβ and/or tau expres...

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Detalles Bibliográficos
Autores principales: Sarparast, Morteza, Hinman, Jennifer, Pourmand, Elham, Vonarx, Derek, Ramirez, Leslie, Ma, Wenjuan, Liachko, Nicole F., Alan, Jamie K., Lee, Kin Sing Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592936/
https://www.ncbi.nlm.nih.gov/pubmed/37873467
http://dx.doi.org/10.1101/2023.10.02.560527