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Localized synthesis of molecular chaperones sustains neuronal proteostasis

Neurons are challenged to maintain proteostasis in neuronal projections, particularly with the physiological stress at synapses to support intercellular communication underlying important functions such as memory and movement control. Proteostasis is maintained through regulated protein synthesis an...

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Detalles Bibliográficos
Autores principales: Alecki, Celia, Rizwan, Javeria, Le, Phuong, Jacob-Tomas, Suleima, Xu, Stella, Minotti, Sandra, Wu, Tad, Durham, Heather, Yeo, Gene W., Vera, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592939/
https://www.ncbi.nlm.nih.gov/pubmed/37873158
http://dx.doi.org/10.1101/2023.10.03.560761