Predicting the effect of CRISPR-Cas9-based epigenome editing

Epigenetic regulation orchestrates mammalian transcription, but functional links between them remain elusive. To tackle this problem, we here use epigenomic and transcriptomic data from 13 ENCODE cell types to train machine learning models to predict gene expression from histone post-translational m...

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Detalles Bibliográficos
Autores principales: Batra, Sanjit Singh, Cabrera, Alan, Spence, Jeffrey P., Hilton, Isaac B., Song, Yun S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592942/
https://www.ncbi.nlm.nih.gov/pubmed/37873127
http://dx.doi.org/10.1101/2023.10.03.560674

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592942/
https://www.ncbi.nlm.nih.gov/pubmed/37873127
http://dx.doi.org/10.1101/2023.10.03.560674

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