The DNA helicase FANCJ (BRIP1) functions in Double Strand Break repair processing, but not crossover formation during Prophase I of meiosis in male mice

During meiotic prophase I, recombination between homologous parental chromosomes is initiated by the formation of hundreds of programmed double-strand breaks (DSBs), each of which must be repaired with absolute fidelity to ensure genome stability of the germline. One outcome of these DSB events is t...

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Detalles Bibliográficos
Autores principales: Horan, Tegan S., Ascenção, Carolline F. R., Mellor, Christopher A., Wang, Meng, Smolka, Marcus B., Cohen, Paula E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592954/
https://www.ncbi.nlm.nih.gov/pubmed/37873301
http://dx.doi.org/10.1101/2023.10.06.561296

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592954/
https://www.ncbi.nlm.nih.gov/pubmed/37873301
http://dx.doi.org/10.1101/2023.10.06.561296

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