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The DNA helicase FANCJ (BRIP1) functions in Double Strand Break repair processing, but not crossover formation during Prophase I of meiosis in male mice
During meiotic prophase I, recombination between homologous parental chromosomes is initiated by the formation of hundreds of programmed double-strand breaks (DSBs), each of which must be repaired with absolute fidelity to ensure genome stability of the germline. One outcome of these DSB events is t...
Autores principales: | Horan, Tegan S., Ascenção, Carolline F. R., Mellor, Christopher A., Wang, Meng, Smolka, Marcus B., Cohen, Paula E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592954/ https://www.ncbi.nlm.nih.gov/pubmed/37873301 http://dx.doi.org/10.1101/2023.10.06.561296 |
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