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Systemic pharmacological suppression of neural activity reverses learning impairment in a mouse model of Fragile X syndrome
The enhancement of associative synaptic plasticity often results in impaired rather than enhanced learning. Previously, we proposed that such learning impairments may result from saturation of the plasticity mechanism making it unavailable to be recruited at the appropriate synapses to support learn...
Autores principales: | Shakhawat, Amin Md, Foltz, Jacqueline G, Nance, Adam B., Bhateja, Jaydev, Raymond, Jennifer L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592955/ https://www.ncbi.nlm.nih.gov/pubmed/37873217 http://dx.doi.org/10.1101/2023.10.05.561013 |
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